Figure 5

GFP-TM1 incorporation reduces viral yield and gp160 processing. Immature (circles) and mature (squares) HIV-1 bearing different levels of GFP-TM1 and ΔCT were generated together with WT virus. 1X stands for 100% GFP-TM1 plasmid input. Error bars indicate the SEM. A). Viral yield (Gag per ml) is normalized to the yield of ΔCT virus. B). Ratio of processed Env (gp120) to unprocessed Env (gp160 for WT Env; gp140 for ΔCT Env) is plotted.