Figure 5

NTD-CTD CA mutant capsids fail to abrogate rest riction by TRIMCyp. OMK cells were co-inoculated with fixed amount (5 ng) of HIV-GFP and the indicated quantities of CA mutant viruses. (A) and (B) are separated for clarity, while (C) and (D) show abrogation activity for the mutants in the wild type and the CA-NC cleavage mutant background, respectively. The values shown are the average of duplicate determinations and are representative of two independent experiments.