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Figure 5 | Retrovirology

Figure 5

From: Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus

Figure 5

Schematic outline of the possible roles of viral dose and the presence of microlesions in the effect of seminal attachment factors on sexual transmission of SIV and HIV-1. Viral particles are indicated as black dots, mucus as pink line and the multi-layered vaginal epithelium by dashed lines. Infection of viral target T cells is indicated by the “+” symbol. Please note that this simplified model needs to be challenged in experimental studies.

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