Allosteric induction of the CD4-bound conformation of HIV-1 Gp120

Retrovirology

Table 1 Sequences of affinity-selected phages from gp120 CDC451 screens

The biased random mutagenesis library was screened using standard or stringent conditions as indicated (see Methods). Hundreds of potential gp120 CDC451 binding clones were obtained and confirmed for gp120 binding, the sequences of a collection of which are given above. *The sequence of 2A6 peptide. **The sequence of m2-peptide (see Figure 2). For convenience, the constant first and last cysteine residues as well as residues of a common motif (xRxDLPxWAxxx) are shown in bold.

ISSN: 1742-4690