Figure 5
From: Dual-acting stapled peptides target both HIV-1 entry and assembly
Turbidity assay results showing the effects of CA-binding to staple peptides on in vitro capsid assembly. Compound: CA ratios and initial rates [millioptical density units (mOD)] per minute, reported as the mean ± standard deviation from three experiments) are as follows: red, 2:1 NYAD-401 (does not bind CA) (223 ± 32.5 mOD/min); black, 1.2uL DMSO control (216 ± 6.23 mOD/min); blue, 2:1 NYAD-67 (205 ± 18.89 mOD/min); green, 2:1 NYAD-66 (166 ± 18.91 mOD/min); orange, 2:1 NYAD-36 (158 ± 24.71 mOD/min).