Skip to main content

Table 2 Sequence identity and entry efficiency of V1V2 inter- and intrasubtypes chimeras

From: Genetic diversity of the highly variable V1 region interferes with Human Immunodeficiency Virus type 1 envelope functionality

  

Sequence identity (%)

Viral entry (%)

SD (%)

Intersubtype

A/B

51.2

141.5

52.2

 

A/C

56.4

29.1

9.2

 

A/G

48.8

72.5

23.0

 

B/C

46.4

1.1

1.0

 

B/C3

45.7

0.5

0.3

 

B/G

47.5

3.2

3.6

Intrasubtype

A/A1

66.7

69.4

38.6

 

A/A2

62.8

115.9

20.1

 

C/C1

60.0

1.2

0.6

 

C/C2

50.0

2.8

1.5

 

C/C3

57.5

0.9

0.6

 

G/G1

54.1

257.1

27.4

  1. In all cases, the values are given relative to those observed for the corresponding wild-type receiver protein. The results for viral entry represent the mean values derived from 3 to 5 independent experiments. SD, standard deviation.