Skip to main content

Table 2 IQP-0528 levels in macaque samples

From: Novel preclinical models of topical PrEP pharmacodynamics provide rationale for combination of drugs with complementary properties

 

Macaques

 

Mean ± SEM

 

PMD2

PKP1

PHC2

PTE2

 

CVL

D7

1490

1290

730

1930

1360 ± 249

D14

1600

510

600

1050

940 ± 250

Cervical tissue

Proximal D7

1.03

1.01

6.16

5.24

3.36 ± 1.36

Proximal D14

33.32

36.68

12.46

29.87

28.08 ± 5.39

Distal D7

0.45

0.66

0.79

1.50

0.85 ± 0.23

 

Distal D14

28.95

2.38

5.66

21.62

14.65 ± 6.35

  1. IQP-0528 concentration in cervicovaginal lavage (CVL) samples (μg/mL) or in proximal or distal cervical biopsy tissue samples (ng/mg of tissue).
Back to article page

Retrovirology

ISSN: 1742-4690

Contact us