Table 3 Anti-HIV-1 restriction factor mRNA relative copy number 1
From: Expression profile of host restriction factors in HIV-1 elite controllers
| Â | HIV negative controls | Elite controllers | ART-suppressed | Non-controllers |
|---|---|---|---|---|
APOBEC3A | 9.45 ± 2.3 | 7.95 ± 3.2 | 7.25 ± 1.6 | 10.23 ± 2.9 |
APOBEC3B | 2.76 ± 0.5 | 3.230.8 | 4.91 ± 1.2 | 11.65 ± 2.7 |
APOBEC3C | 419.62 ± 42.3 | 509.99 ± 38.9 | 393.1 ± 27.1 | 545.81 ± 49.5 |
APOBEC3D | 96.42 ± 12.4 | 125.44 ± 11.2 | 92.44 ± 8.7 | 139.17 ± 14 |
APOBEC3F | 2 ± 0.3 | 2.73 ± 0.4 | 1.88 ± 0.2 | 3.35 ± 0.4 |
APOBEC3G | 66.29 ± 9 | 87.22 ± 7.4 | 67.16 ± 6.6 | 84.02 ± 9.7 |
APOBEC3H | 10.88 ± 2.2 | 12.89 ± 2.6 | 12.53 ± 1.6 | 16.74 ± 3 |
BST2 | 59.15 ± 9.1 | 81.19 ± 9.9 | 62.31 ± 8.5 | 108.6 ± 16.5 |
CDKN1A (P21) | 90.75 ± 25.8 | 74.43 ± 41.1 | 77.39 ± 29.9 | 48.6 ± 11.5 |
CTR9 | 170.92 ± 11 | 175.81 ± 11.1 | 146.7 ± 5.6 | 164.3 ± 8.1 |
EIF2AK2 | 416.56 ± 11.8 | 359.92 ± 14.5 | 434.52 ± 11.5 | 805.28 ± 8.1 |
HERC5 | 179.53 ± 28.7 | 129.72 ± 9.1 | 146.37 ± 22.2 | 250.33 ± 20.9 |
IFITM1 | 12102.96 ± 624.2 | 13852.2 ± 778 | 11789.6 ± 1190 | 18163.4 ± 1222.4 |
IFITM2 | 2325.19 ± 161.3 | 2442.24 ± 178 | 2256.65 ± 195.9 | 2903.74 ± 239.8 |
IFITM3 | 66.43 ± 17.1 | 85.81 ± 13.6 | 97.44 ± 16 | 143.82 ± 20.9 |
ISG15 | 17.85 ± 3.7 | 16.82 ± 2.3 | 26.91 ± 8.3 | 56.58 ± 9.1 |
MOV10 | 151.25 ± 10.6 | 162.57 ± 14.7 | 137.56 ± 10.6 | 190.16 ± 9.9 |
PAF1 | 95.25 ± 3.6 | 98.88 ± 6.4 | 87.55 ± 4.2 | 102.38 ± 6.4 |
RNASEL | 34.34 ± 2.9 | 37.96 ± 3.5 | 31.75 ± 2.9 | 34.32 ± 2.5 |
RSAD2 (Viperin) | 29.86 ± 12.8 | 23.2 ± 2.5 | 37.11 ± 11.2 | 102.81 ± 15.4 |
RTF1 | 322.64 ± 18.2 | 323.08 ± 24.1 | 276.97 ± 16.5 | 322.93 ± 15.7 |
SAMHD1 | 1322.37 ± 159.4 | 1420.63 ± 95.8 | 1470.53 ± 78 | 1685.26 ± 92.4 |
SLFN11 | 92.4 ± 10.1 | 80.98 ± 10.3 | 54.64 ± 3.4 | 57.44 ± 4.6 |
TRIM11 | 85.09 ± 7.4 | 82.25 ± 6.3 | 72.81 ± 6.4 | 97.63 ± 10.1 |
TRIM14 | 296.58 ± 25.6 | 351.14 ± 26.8 | 302.04 ± 24 | 460.72 ± 42.5 |
TRIM19 (PML) | 180.3 ± 14.5 | 203.55 ± 16.1 | 169.58 ± 13 | 267.52 ± 27.6 |
TRIM21 | 128.44 ± 8.9 | 133.74 ± 8.6 | 120.86 ± 10.3 | 148.63 ± 11.1 |
TRIM22 | 1547.88 ± 124.4 | 1457.21 ± 93.4 | 1418.98 ± 78.9 | 2049.2 ± 89.4 |
TRIM26 | 197.14 ± 16.2 | 188.7 ± 13.3 | 146.16 ± 14 | 201.34 ± 18.4 |
TRIM28 | 545.06 ± 27 | 562.97 ± 36.6 | 499.71 ± 32.2 | 527.79 ± 28.5 |
TRIM32 | 178.17 ± 12.7 | 173.69 ± 14 | 139.87 ± 7.3 | 180.89 ± 16.9 |
TRIM5 | 68.18 ± 10.6 | 86.44 ± 7.2 | 77.97 ± 5.7 | 108.67 ± 6.8 |