|  | IC50
a (ng/ml) |
---|
 |  | U87.CD4.CCR5 cells | U87.CD4.CXCR4 cells |
---|
Virus strain | Co-receptor Use | SCH-C | RANTES | LD78β | AMD3100 | SDF-1 |
---|
BaL
| R5 | 58 | >1000 | >1000 | NA | NA |
NL4.3
| X4 | NA | NA | NA | 3.6 | >1000 |
HE
| R5/X4 | 0.4 | 200 | 18 | 3.3 | >1000 |
-
a Effect of AMD3100 and SCH-C and the chemokines SDF-1, RANTES and LD78β on the replication of laboratory HIV-1 strains BaL, NL4.3 and HE. Virus yield was monitored by p24 HIV-1 Ag ELISA o cell-free supernatant at 4–5 days after infection. NA = Not applicable