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Figure 1 | Retrovirology

Figure 1

From: The sequence of the CA-SP1 junction accounts for the differential sensitivity of HIV-1 and SIV to the small molecule maturation inhibitor 3-O-{3',3'-dimethylsuccinyl}-betulinic acid

Figure 1

Comparison of HIV-1 and SIVmac239 CA-SP1 Gag cleavage sites, and substitution mutants analyzed in this study. The HIVm2 mutant contains the P2 and P1 residues of SIV, while the SIVm2 and SIVm3 mutants contain substitutions of the corresponding HIV-1 amino acids. HIV-1 and SIV mutants were created in the pNL4-3 and pBR239E full-length molecular clones, respectively.

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