Fig. 6
From: Attenuation of reverse transcriptase facilitates SAMHD1 restriction of HIV-1 in cycling cells
HIV-1 cDNA levels synthesised under different conditions Cycling or differentiated U937 cells transduced with WT SAMHD1 (black circles), T592C (blue diamonds) or T592D (red squares) mutants were infected with WT HIV-1 or RT Q151N mutant VLPs for 48 h. Late viral reverse transcription products were detected by qPCR. Three technical repeats are shown, with the error bars representing SD. The dashed line represents the putative threshold for productive infection over restriction