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Fig. 1 | Retrovirology

Fig. 1

From: An endogenous lentivirus in the germline of a rodent

Fig. 1

Phylogenetic relationships within the Lentivirus genus. Maximum likelihood phylogeny showing reconstructed evolutionary relationships between all known lentivirus species, including the extinct species represented by endogenous lentiviruses. Brackets to the left indicate proposed subgroupings within genus Lentivirus. Coloured circles adjacent virus taxa labels indicate the ecological characteristics of the associated host species (grassland-dwelling or arboreal) as shown in the key top right. The phylogeny is midpoint rooted for display purposes and was reconstructed using a multiple sequence alignment spanning 1405 amino acid residues of the Gag-Pol polyprotein and the RT-Rev substitution model [43]. The scale bar shows evolutionary distance in substitutions per site. Asterisks indicate nodes with bootstrap support > 70% (1000 replicates). Arrows indicate genome evolution events as follows (1) acquisition of tat, rev and vif genes (putatively); (2) loss of dUTPase; (3) partial loss of dUTPase. Abbreviations: FIV = Feline immunodeficiency virus; SRLV = small ruminant lentivirus; BIV = Bovine immunodeficiency virus; RELIK = Rabbit endogenous lentivirus type K; EIAV = equine infectious anaemia virus; MELV = Mustelidae endogenous lentivirus; SIV = Simian immunodeficiency virus; PSIV = Prosimian immunodeficiency virus; DELV = Dermopteran endogenous lentivirus; SpELV = springhare endogenous lentivirus

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