Table 1 Non-parametric Friedman test on HERV and cytokines expression in PBMCs stimulated in vitro with IL-2/PHA
|  |  | HERV-H | HERV-K | HEMO | HERV-W | pHERV-W | IL-1β | IL-6 | IL-8 | IL-10 | TNF-α | INF-γ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Children | T0 vs NS | 0.001 | – | – | – | 0.001 | 0.001 | 0.005 | – | – | 0.011 | – |
CI | T0 vs ST | – | – | – | 0.004 | – | < 0.001 | – | – | – | < 0.001 | – |
|  | NS vs ST | – | – | – | 0.001 | – | – | – | – | – | – | – |
Children | T0 vs NS | – | – | – | – | – | – | – | – | – | – | – |
ASD | T0 vs ST | 0.002 | < 0.001 | 0.002 | – | – | < 0.001 | < 0.001 | – | – | < 0.001 | < 0.001 |
|  | NS vs ST | – | < 0.001 | 0.003 | – | – | < 0.001 | < 0.001 | – | – | 0.001 | 0.002 |
Mothers | T0 vs NS | – | 0.003 | 0.004 | – | – | – | – | – | – | – | – |
CI | T0 vs ST | – | – | 0.006 | – | – | – | – | – | – | – | – |
|  | NS vs ST | – | – | – | – | – | – | – | – | - | – | – |
Mothers | T0 vs NS | – | 0.012 | – | – | – | – | – | – | – | 0.003 | – |
ASD | T0 vs ST | – | – | – | – | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
|  | NS vs ST | – | – | – | – | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.001 | < 0.001 |
Fathers | T0 vs NS | – | – | – | – | – | – | – | – | – | - | – |
CI | T0 vs ST | – | – | – | – | – | – | – | – | – | - | – |
|  | NS vs ST | – | – | – | – | – | – | – | – | – | - | – |
Fathers | T0 vs NS | – | – | – | < 0.001 | – | – | – | – | – | - | – |
ASD | T0 vs ST | – | – | – | 0.006 | – | – | – | – | – | - | – |
|  | NS vs ST | 0.020 | – | – | – | 0.008 | – | – | – | – | - | – |