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Fig. 4 | Retrovirology

Fig. 4

From: Repression of HIV-1 reactivation mediated by CRISPR/dCas9-KRAB in lymphoid and myeloid cell models

Fig. 4

CRISPR sgRNAs repress HIV-1 RNA molecule expression in U1 cells. A Basal expression of HIV-1 RNA molecules in untreated U1 (NT, LTR1, LTR4, LTR5) cells. B HIV-1 RNA molecules in U1 (NT, LTR1, LTR4, LTR5) cells reactivated with 1 µM of IngB 48 h. The statistical analysis was performed using one-way ANOVA comparing mean of NT with LTR1 to LTR5 (*p < 0.05; **p < 0.003***, p < 0.0003). The mean values of two technical measures of three independent biological experiments are shown

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