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Fig. 3 | Retrovirology

Fig. 3

From: Anti-inflammatory effects of recreational marijuana in virally suppressed youth with HIV-1 are reversed by use of tobacco products in combination with marijuana

Fig. 3

Significantly perturbed pathways in study groups and DEG within Interferon and ERK5 signaling pathways. a Significantly perturbed pathways were based on Ingenuity Pathway Analysis (IPA) using p ≤ 0.001 and Z score ≥ + 1 for activation (blue-filled) or p ≤ 0.001 and Z score ≤ -1 for suppression (grey-filled). VL+, > 50 viral copies per ml plasma; VL−, ≤ 50 viral copies per ml plasma. Study groups: II, VL+ no substance; III—V, VL− with III, no substance; IV, marijuana only; and V, marijuana plus tobacco. a Pathway full name: #10, Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses. b, c DEG within the Interferon [#1] and the ERK5 [#9] Signaling Pathways (down-regulated, green-filled; up-regulated, red-filled). Boxes: blue, DEG specific for Group IV; brown, DEG specific for Group V

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Retrovirology

ISSN: 1742-4690

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