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Fig. 2 | Retrovirology

Fig. 2

From: Anti-inflammatory effects of recreational marijuana in virally suppressed youth with HIV-1 are reversed by use of tobacco products in combination with marijuana

Fig. 2

Principal component analysis (PCA). PCA based on the top 40% highly variable DEG probes (2634 of 6586) representing the top 40% highly variable unique DEG (929 of 2322) separated the 88 study participants into three clusters when using PC2 and PC3, which accounted for 12.1% or 6.1% of the total variance, respectively. Symbols: circles, participants; ellipses, participant clusters. Circle colors: gray-filled, Reference Group (non-substance using YWOH, n = 25); gray-open, Group I (YWOH using a combination of alcohol, marijuana and tobacco, n = 9); pink-filled, Group II [non-substance using YWH who had detectable plasma virus on ART (VL > 50 copies/ml), n = 8]; blue-filled, Group III [non-substance using YWH who achieved viral suppression on ART (VL ≤ 50 copies/ml), n = 19]; blue-open: Group IV (virally suppressed YWH using marijuana alone, n = 8); pink-open: Group V (virally suppressed YWH using marijuana plus tobacco, n = 19)

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