Skip to main content
Fig. 2 | Retrovirology

Fig. 2

From: Immunoescape of HIV-1 in Env-EL9 CD8 + T cell response restricted by HLA-B*14:02 in a Non progressor who lost twenty-seven years of HIV-1 control

Fig. 2

Estimation of viral evolution in the C2-V5 region during the patient follow-up. a The C2-V5 env diversity (y axis) was calculated as the number of base substitutions per site and averaging from all sequence pairs within each group and for each variant. For statistical evaluations, we used the Tukey's multiple comparisons test considering significance at the 95% (p-values < 0.05 were assumed as statistically significant). b The env divergence (y axis) was estimated as the pairwise temporal distance from A, B1 and B2 time points (x axis) to the corresponding time to the MRCA. c and d panels show B2 C2-V5 genetic diversity c and genetic divergence d (y axis) over time (x axis). The plots include the global diversity (squares), number of substitutions per site d (circles), number of sites with synonymous substitution per synonymous site (dS) (triangles) and number of sites with nonsynonymous substitutions per nonsynonymous site (dN) (square) from averaging over all sequence pairs between groups

Back to article page

Retrovirology

ISSN: 1742-4690

Contact us