From: HIV-1 capsid variability: viral exploitation and evasion of capsid-binding molecules
Gene name | Gene ID | Also known as | Gene description | Strategy for gene discovery | References |
---|---|---|---|---|---|
CPSF6 | 11052 | Cleavage and polyadenylation specific factor 6 | Subunit of a cleavage factor required for 3′ RNA cleavage and polyadenylation processing | Expression cloning | [93] |
Cyclophilin A | 5478 | PPIA | Member of the peptidyl-prolyl cis–trans isomerase (PPIase) family | GAL4 two-hybrid screen | [104] |
FEZ1 | 9638 | Fasciculat ion and elongation protein zeta 1 | Ortholog of the Caenorhabditis elegans unc-76 gene that is necessary for axonal bundling and elongation within axon bundles | RNAi-mediated inhibition | [100] |
KIF5B | 3799 | Kinesin family member 5b | Member of the kinesin family protein with ATPase that acts as a microtubule motor | Pharmacological and RNAi-mediated inhibition | [125] |
MX2 | 4600 | MXB, MX dynamin like GTPase | Member of both the dynamin family and the family of large GTPases | Transcriptional profiling | |
NUP153 | 9972 | Nucleoporin 153 | Nucleoporin carrying characteristic XFXFG pentapeptides | Large-scale RNAi screening | |
NUP358 | 5903 | RANBP2 | A large RAN-binding protein that localizes to the nuclear pore complex | Large-scale RNAi screening | |
SUN2 | 25777 | Sad1 and unc84 domain containing 2 | An inner nuclear membrane protein with a major role in nuclear-cytoplasmic connection | Sun2-null mouse cells | |
TNPO3 | 23534 | Transportin (TRN) 3/TRN-SR2 | Nuclear transport receptor for serine/arginine-rich proteins | Yeast-two-hybrid and siRNA screens | |
TRIM5α | 85363 | Tripartite motif containing 5α | Member of the tripartite motif (TRIM) family | Expression cloning | [230] |
TRIM34 | 53840 | Tripartite motif containing 34 | Member of the TRIM family | HIV-CRISPR screening | [290] |