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Fig. 2 | Retrovirology

Fig. 2

From: A novel class III endogenous retrovirus with a class I envelope gene in African frogs with an intact genome and developmentally regulated transcripts in Xenopus tropicalis

Fig. 2

The complete nucleotide and deduced amino acid sequence of the XtERV-S proviral genome. The sequence is shown from the beginning of the 5′ U3 region to the end of the 3′ U5. The LTR sequence is in black italics and its inverse repeats are double underlined. The gag, pol and env ORFs are in red, blue and purple, respectively, and termination codons are marked by an asterisk. The Orf-x2 sequence is in light green. The positions of the functional motifs are bolded and highlighted and include the following in order: PBS (primer binding site); basic regions of Gag; MHR (major homology region); GQR motif; PSAP late domain; PR (protease); RT/RNH (reverse transcriptase/RNase H); CWIC (isomerase domain); furin site; ISD (immunosuppressive domain); MSD (membrane spanning domain); PPT (polypurine tract); polyA (polyadenylation signal). Arrows indicate the splice donor and acceptor sites. The dUTPase region of pol is underlined and bolded

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