HIV-1 capsid exploitation of the host microtubule cytoskeleton during early infection

Retrovirology

Table 1 MT regulatory factors that interact with HIV-1 capsid and their effects on early stages of infection

Gene name (NCBI)^a	Gene ID (NCBI)^a	Early steps of HIV-1 life cycle affected	References
PDZD8: PDZ domain containing protein 8	118987	Reverse transcription and capsid stability	[37, 38]
BICD2: Bicaudal D homology 2	23299	Retrograde trafficking and uncoating	[31, 97]
FEZ1: Fasciculation and elongation protein zeta 1	9638	Retrograde trafficking and uncoating	[69, 96]
MARK2: MT affinity regulating kinase 2	2011	Retrograde trafficking and uncoating	[69]
MAP1A: MT associated protein 1A	4130	Nuclear translocation	[69]
MAP1S: MT associated protein 1S	55201	Nuclear translocation	[64]
DIAPH1 (Dia1): Diaphanous related formin 1	1729	Retrograde trafficking, uncoating and reverse transcription	[42]
DIAPH2 (Dia2):Diaphanous related formin 2	1730	Retrograde trafficking, uncoating and reverse transcription	[42]
CLASP2: Cytoplasmic linker associated protein 2	23122	Retrograde trafficking	[30]
CLIP170: Cytoplasmic linker protein 170	6249	Retrograde trafficking and uncoating	[75]

ISSN: 1742-4690