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Table 2 Linear regression models investigating the relationship between HIV-1 subtype and VRC for West Africa

From: Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa

  Univariate model Multivariate model
  West Africa Cameroon Senegal
Observations 166 77 66
Prob > f  < 0.0001  < 0.0001 0.022
r2 0.290 0.653 0.193
aSubtypes Co-efficient p-value Co-efficient p-value Co-efficient p-value
 A1 − 0.388  < 0.0001 − 0.489  < 0.0001 – –
 A1Gb − 0.190 0.013 − 0.012 0.854 − 0.352 0.010
 A3 − 0.250  < 0.0001 – – − 0.199 0.032
 CRF 11_cpx 0.033 0.691 − 0.006 0.907 – –
 CRF 22_01A1 − 0.038  < 0.0001 − 0.398  < 0.0001 – –
 D 0.093 0.187 0.024 0.681 0.137 0.308
 G − 0.017 0.775 − 0.098 0.223 − 0.067 0.768
Meta data
 Age – – − 0.001 0.629 – –
 Log VL – – 0.033 0.054 – –
 CD4 + count – – – – 0.000 0.137
  1. aCRF02_AG is the reference subtype. bA1G is not a CRF
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Retrovirology

ISSN: 1742-4690

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