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Table 2 Linear regression models investigating the relationship between HIV-1 subtype and VRC for West Africa

From: Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa

 

Univariate model

Multivariate model

 

West Africa

Cameroon

Senegal

Observations

166

77

66

Prob > f

 < 0.0001

 < 0.0001

0.022

r2

0.290

0.653

0.193

aSubtypes

Co-efficient

p-value

Co-efficient

p-value

Co-efficient

p-value

 A1

− 0.388

 < 0.0001

− 0.489

 < 0.0001

–

–

 A1Gb

− 0.190

0.013

− 0.012

0.854

− 0.352

0.010

 A3

− 0.250

 < 0.0001

–

–

− 0.199

0.032

 CRF 11_cpx

0.033

0.691

− 0.006

0.907

–

–

 CRF 22_01A1

− 0.038

 < 0.0001

− 0.398

 < 0.0001

–

–

 D

0.093

0.187

0.024

0.681

0.137

0.308

 G

− 0.017

0.775

− 0.098

0.223

− 0.067

0.768

Meta data

 Age

–

–

− 0.001

0.629

–

–

 Log VL

–

–

0.033

0.054

–

–

 CD4 + count

–

–

–

–

0.000

0.137

  1. aCRF02_AG is the reference subtype. bA1G is not a CRF