Skip to main content
Fig. 3 | Retrovirology

Fig. 3

From: Establishment of a novel diagnostic test algorithm for human T-cell leukemia virus type 1 infection with line immunoassay replacement of western blotting: a collaborative study for performance evaluation of diagnostic assays in Japan

Fig. 3

Serological sensitivity comparison between WB and LIA on WB-indeterminate samples with provirus positivity. To examine the performance of LIA as an alternative confirmatory test in more detail, 110 primary detection-reactive and WB-indeterminate samples with provirus positivity were subjected to LIA. a HTLV-1 antibody sensitivity to p19, p24, gp46, and gp21 of LIA was investigated. Samples that reacted or did not with each antigen were classified according to the band intensity from (−) to (4+) as indicated and depicted in the bar graph. b HTLV-1 antibody sensitivity to gp46 I/II (LIA test) and gp46 (WB test) was evaluated. Reactive/non-reactive samples were classified according to their band intensities from (−) to (3+) and from (−) to (+), respectively, and compared with each other

Back to article page