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Table 3 Protease RF values for L76V mutation

From: Non-active site mutants of HIV-1 protease influence resistance and sensitisation towards protease inhibitors

Genotype

RF

ATV

SQV

IDV

LPV

FB15

 L76

63

74

–

–

 V76

0.9, 2.3, 4.5

3.6, 4.6, 5.8

–

–

GH9

 L76

90

18.6

–

–

 V76

1.2, 1.9, 2.4, 3.2, 3.6

1.2, 1.3, 1.5

–

–

RU1

 V76

2.7

–

–

157

 L76

8.4, 9, 10

–

–

27, 46, 47

iZ2

 V76

4.1

–

59

71

 L76

7.8, 12, 30

–

2.2, 7.9, 10

5.5, 11, 12

  1. Multiple RF measurements for the same protein separated by comma. For each genotype the first row represents the wildtype position as in the original sample and the second row represents the mutation introduced at position 76
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