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Fig. 7 | Retrovirology

Fig. 7

From: HIV-1 Rev interacts with HERV-K RcREs present in the human genome and promotes export of unspliced HERV-K proviral RNA

Fig. 7

Quantitative analysis of HERV-K 3q12.3 proviral transcripts from total and cytoplasmic RNAseq data. a Total and cytoplasmic DESeq2 normalized read counts for HERV-K 3q12.3 provirus, were visualized with IGV. They are shown below a diagram of the genome of the provirus showing the open reading frames and LTRs which contain the RcREs. b The number of normalized reads mapping uniquely to the HERV-K 3q12.3 locus for total and cytoplasmic RNA are plotted for each of the samples transduced with either empty vector (EV), Rev, Tat, both Tat and Rev or Rec. c Quantitation of the data in b showing the fold change in read count relative to the sample transduced with the empty vector (EV)

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