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Table 2 (a) CIMT and (b) carotid distensibility per group

From: Cardiovascular disease risk in an urban African population: a cross-sectional analysis on the role of HIV and antiretroviral treatment

 

HIV-negative

HIV-positive

p

 

ART-naïve

First-line ART

Second-line ART

n = 152

n = 104

n = 87

n = 191

(a) CIMT (mm)

 CCA mean (mm)

0.504 (0.477–0.562)

0.504 (0.470–0.560)

0.521 (0.488–0.564)

0.564 (0.512–0.655)

< 0.001†

 CCA max (mm)

0.575 (0.525–0.669)

0.575 (0.523–0.651)

0.594 (0.554–0.653)

0.667 (0.598–0.756)

< 0.001†

 Plaquea

0

1 (1.0%)

0

5 (2.6%)

0.08

 

n = 133

n = 98

n = 80

n = 163

 

 Bulb max (mm)

0.686 (0.583–0.802)

0.673 (0.542–0.824)

0.717 (0.579–0.797)

0.809 (0.698–0.971)

< 0.001†

 

n  = 148

n = 100

n = 82

n = 184

 

(b) Carotid distensibility (10−6 N−1 m2)

 Pulse pressure (mmHg)

45.5 (38.5–51.0)

42.5 (39.0–50.0)

41.5 (34.5–50.6)

41.5 (36.6–49.5)

0.06

 LD min right CCA (mm)

5.765 (5.331–6.160)

5.813 (5.444–6.102)

5.699 (5.423–6.098)

5.706 (5.421–6.155)

0.932

 LD diff right CCA (mm)

0.633 (0.489–0.784)

0.618 (0.475–0.769)

0.566 (0.451–0.709)

0.530 (0.434–0.632)

< 0.001‡

 Distensibility (10−6 N−1 m2)

36.96 (27.03–48.00)

37.82 (26.75–50.12)

35.91 (27.45–45.04)

31.68 (25.93–40.85)

0.009§

  1. Outcomes in median with IQR
  2. The p-value is based on the Kruskal-Wallis test with post-hoc testing using a Bonferroni correction
  3. ART anti-retroviral therapy, CCA common carotid artery, CIMT carotid artery intima-media thickness, LD luminal diameter, mm millimeter, IQR interquartile range
  4. †p<0.001 for second-line ART vs ART-naïve, second-line ART vs first-line ART and second-line ART vs HIV-negative
  5. ‡p = 0.002 for second-line ART vs ART-naïve and p < 0.001 for second-line ART vs HIV-negative
  6. §p = 0.025 for second-line ART vs ART-naïve and p < 0.036 for second-line ART vs HIV-negative
  7. aMean CCA thickness > 1.0 mm at any angle
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Retrovirology

ISSN: 1742-4690

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