Fig. 3
From: Effect of induced dNTP pool imbalance on HIV-1 reverse transcription in macrophages
Effect of single dC treatment on HIV-1 replication in macrophages. Human primary monocyte-derived macrophages prepared from four healthy donors were cultured with and without a mixture of dC (2.5 mM), and used for each experiment under the same condition described in Fig. 1: a dNTP level measurement, b 2-LTR circle DNA copy number assay, and c p24 level assay with infectious HIV-1 89.6 were conducted described in Fig. 1. “+” indicates the treated dCTP. NT no dN treatment. The data are the mean of three independent experiments and error bars represent the standard deviation from the mean