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Fig. 1 | Retrovirology

Fig. 1

From: Silencers of HTLV-1 and HTLV-2: the pX-encoded latency-maintenance factors

Fig. 1

Diagrams of the HTLV-1 and HTLV-2 proviral genomes and their products. a The coding regions of the HTLV-1 genome are represented by filled boxes. The antisense HBZ-SP1 product is shown at the bottom with an arrow indicating its transcriptional initiation site from the 3′ LTR. b The HTLV-2 genome and its products. The coding region for the antisense-encoded APH-2 protein is indicated. The conserved pX nucleotide sequences are indicated in a and b. The pX-encoded latency factors discussed in this review are represented by colored boxes. HBZ-SP1 HTLV-1 basic domain/leucine zipper-spliced-1 isoform, APH-2 antisense protein of HTLV-2, LTR long terminal repeat

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