Fig. 3From: Bovine leukemia virus proviral load is more strongly associated with bovine major histocompatibility complex class II DRB3 polymorphism than with DQA1 polymorphism in Holstein cow in JapanAssociation study to determine the significance of detection frequency of the BoLA-DQA1 allele compared with 672 alleles from low-risk spreaders and 1126 alleles from high-risk spreaders. The same samples as described in Fig. 1 were genotyped for BoLA-DQA1 alleles with PCR-sequence based typing (SBT) developed previously [39]. Fisher’s exact test was performed for estimating p values and odds ratios (ORs) were used to detect the association of BoLA-DQA1 alleles with BLV proviral load. The X-axis shows the allele number for BoLA-DQA and Y-axis shows the minus multiplied common logarithm for p values. The alleles with p values < 0.00357 (0.05/14 alleles) were determined as resistant when OR > 1 and susceptible when OR < 1Back to article page