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Fig. 3 | Retrovirology

Fig. 3

From: Bovine leukemia virus proviral load is more strongly associated with bovine major histocompatibility complex class II DRB3 polymorphism than with DQA1 polymorphism in Holstein cow in Japan

Fig. 3

Association study to determine the significance of detection frequency of the BoLA-DQA1 allele compared with 672 alleles from low-risk spreaders and 1126 alleles from high-risk spreaders. The same samples as described in Fig. 1 were genotyped for BoLA-DQA1 alleles with PCR-sequence based typing (SBT) developed previously [39]. Fisher’s exact test was performed for estimating p values and odds ratios (ORs) were used to detect the association of BoLA-DQA1 alleles with BLV proviral load. The X-axis shows the allele number for BoLA-DQA and Y-axis shows the minus multiplied common logarithm for p values. The alleles with p values < 0.00357 (0.05/14 alleles) were determined as resistant when OR > 1 and susceptible when OR < 1

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