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Fig. 7 | Retrovirology

Fig. 7

From: Interaction of HIV-1 integrase with polypyrimidine tract binding protein and associated splicing factor (PSF) and its impact on HIV-1 replication

Fig. 7

Docking structure of a full length HIV-1 Integrase (in green)-dsDNA (in stick) complex with PSF (in purple), with inset of DDE motif of CCD-domain, showing different residues of PSF and HIV-1 interacting with dsDNA, b full length HIV-1 Integrase (in green) with PSF (in purple), in inset, the DDE motif was found to be occupied with other residues, here D386 (in yellow stick) of PSF presents near D64 of HIV IN directly interacts with Mg+2 ions

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