From: Functional analysis of the secondary HIV-1 capsid binding site in the host protein cyclophilin A
CA | CA hexamer | CA tube | Native capsid | |
---|---|---|---|---|
WT | 26.8 | 23.7 | 14.5 ± 5 | 10.7 ± 0.7 |
A25D | 22.6 | 20.8 | 17.2 ± 4.8 | 8.7 ± 2.1 |
K27D | 28.5 | 21.7 | 17.7 ± 6.7 | n.d. |
P29K | 20.6 | 21 | 16.4 ± 3.8 | n.d. |
K30D | 37.9 | 35.7 | 17 ± 9.2 | n.d. |