Fig. 9
From: RNA-induced epigenetic silencing inhibits HIV-1 reactivation from latency
Model of HIV-1 promoter control through RNA-induced epigenetic silencing and the effect of TNF. The two nucleosomes, nuc-0 and nuc-1, are comprised of a histone 1 linker (gray) and four histone pairs (shown in green, orange, purple, and pink) that generate the histone octamer. Activator protein 1 (AP-1), COUP-TF, upstream stimulatory factor 1/2 (USF 1/2), nuclear factor of activated T cells (NFAT), glucocorticoid receptor (GR), transcription factor II-I (TF II-I), Yin Yang 1 (YY1), NF-κB, specificity protein 1 (SP1), late SV40 factor (LSF), specificity protein 3 (SP3)