Skip to main content
Fig. 8 | Retrovirology

Fig. 8

From: Cell surface ectodomain integrity of a subset of functional HIV-1 envelopes is dependent on a conserved hydrophilic domain containing region in their C-terminal tail

Fig. 8

Infectivity and neutralization assays of 4-2.J41 mutant Env pseudotyped viruses. a Infectivity of 4-2.J41 Env wild type and deletion mutant pseudoviruses using TZM-bl reporter based cell assay. b IC50 values of 4-2.J41 wild type and deletion mutant Env pseudotyped viruses with the cleavage non-specific bNAb VRC01, glycan-dependent and conformational bNAb, PG9, trimer-selective and cleavage-specific bNAb, PGT151, MPER-directed bNAbs, 10E8 and 4E10. c IC50 values of 4-2.J41 wild type and deletion mutant Env pseudotyped viruses with bNAbs, PGT121 and PGT145 (left panel) and non-NAbs F105 and 17b at 37 and 4 °C (right panel)

Back to article page

Retrovirology

ISSN: 1742-4690

Contact us