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Fig. 3 | Retrovirology

Fig. 3

From: Global phosphoproteomics of CCR5-tropic HIV-1 signaling reveals reprogramming of cellular protein production pathways and identifies p70-S6K1 and MK2 as HIV-responsive kinases required for optimal infection of CD4+ T cells

Fig. 3

Kinase substrate enrichment analysis (KSEA) of HIV and HIV + MVC signaling. Only kinases with at least 3 identified substrates are included. Red colored cells indicate a positive normalized kinase score, which corresponds to a kinase with upregulated signaling output in the treatment group relative to control. The inverse (blue color) represents kinases with downregulated output. a Comparison between HIV or HIV + MVC with the extracellular vesicle (EV) control. b Comparison between HIV and HIV + MVC

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Retrovirology

ISSN: 1742-4690

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