Fig. 4From: HIV latency reversing agents act through Tat post translational modificationsJQ1 affects alternative splicing by modulating hnRNP protein levels. Alternative splicing pattern of CD46 (a), ATF2 (b) and ABI1 (c) in HEK293T cells following 24 h of JQ1 (1 μM) or DMSO treatment. Inclusion and exclusion of exons are indicated on the right of the gel with white boxes, while grey boxes represent constitutively included exons. NTC = No Template Control, -RT corresponds to minus reverse transcriptase control. d Western Blot analysis of splicing factors following treatment with JQ1 or DMSO diluent controlBack to article page