TY - CHAP AU - Petropoulos, C. ED - Coffin, J. M. ED - Hughes, S. H. ED - Varmus, H. E. PY - 1997 DA - 1997// TI - Retroviral taxonomy, protein structures, sequences, and genetic maps BT - Retroviruses PB - Cold Spring Harbor Laboratory Press CY - New York ID - Petropoulos1997 ER - TY - JOUR AU - Jacks, T. AU - Power, M. D. AU - Masiarz, F. R. AU - Luciw, P. A. AU - Barr, P. J. AU - Varmus, H. E. PY - 1988 DA - 1988// TI - Characterization of ribosomal frameshifting in HIV-1 gag-pol expression JO - Nature VL - 331 UR - https://doi.org/10.1038/331280a0 DO - 10.1038/331280a0 ID - Jacks1988 ER - TY - JOUR AU - Freed, E. O. PY - 2015 DA - 2015// TI - HIV-1 assembly, release and maturation JO - Nat Rev Microbiol VL - 13 UR - https://doi.org/10.1038/nrmicro3490 DO - 10.1038/nrmicro3490 ID - Freed2015 ER - TY - JOUR AU - Huang, M. AU - Martin, M. A. PY - 1997 DA - 1997// TI - Incorporation of Pr160(gag-pol) into virus particles requires the presence of both the major homology region and adjacent C-terminal capsid sequences within the Gag-Pol polyprotein JO - J Virol VL - 71 ID - Huang1997 ER - TY - JOUR AU - Smith, A. J. AU - Srinivasakumar, N. AU - Hammarskjöld, M. L. AU - Rekosh, D. PY - 1993 DA - 1993// TI - Requirements for incorporation of Pr160gag-pol from human immunodeficiency virus type 1 into virus-like particles JO - J Virol VL - 67 ID - Smith1993 ER - TY - JOUR AU - Srinivasakumar, N. AU - Hammarskjöld, M. L. AU - Rekosh, D. PY - 1995 DA - 1995// TI - Characterization of deletion mutations in the capsid region of human immunodeficiency virus type 1 that affect particle formation and Gag-Pol precursor incorporation JO - J Virol VL - 69 ID - Srinivasakumar1995 ER - TY - JOUR AU - Park, J. AU - Morrow, C. D. PY - 1992 DA - 1992// TI - The nonmyristylated Pr160gag-pol polyprotein of human immunodeficiency virus type 1 interacts with Pr55gag and is incorporated into viruslike particles JO - J Virol VL - 66 ID - Park1992 ER - TY - JOUR AU - Lee, S. K. AU - Potempa, M. AU - Swanstrom, R. PY - 2012 DA - 2012// TI - The choreography of HIV-1 proteolytic processing and virion assembly JO - J Biol Chem VL - 287 UR - https://doi.org/10.1074/jbc.R112.399444 DO - 10.1074/jbc.R112.399444 ID - Lee2012 ER - TY - CHAP AU - Swanstrom, R. AU - Wills, J. W. ED - Coffin, J. M. ED - Hughes, S. H. ED - Varmus, H. E. PY - 1997 DA - 1997// TI - Synthesis, assembly, and processing of viral proteins BT - Retroviruses PB - Cold Spring Harbor Laboratory Press CY - New York ID - Swanstrom1997 ER - TY - JOUR AU - Pettit, S. C. AU - Moody, M. D. AU - Wehbie, R. S. AU - Kaplan, A. H. AU - Nantermet, P. V. AU - Klein, C. A. AU - Swanstrom, R. PY - 1994 DA - 1994// TI - The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions JO - J Virol VL - 68 ID - Pettit1994 ER - TY - JOUR AU - Peng, C. AU - Ho, B. K. AU - Chang, T. W. AU - Chang, N. T. PY - 1989 DA - 1989// TI - Role of human immunodeficiency virus type 1-specific protease in core protein maturation and viral infectivity JO - J Virol VL - 63 ID - Peng1989 ER - TY - JOUR AU - Liao, W. H. AU - Wang, C. T. PY - 2004 DA - 2004// TI - Characterization of human immunodeficiency virus type 1 Pr160 gag-pol mutants with truncations downstream of the protease domain JO - Virology VL - 329 UR - https://doi.org/10.1016/j.virol.2004.08.010 DO - 10.1016/j.virol.2004.08.010 ID - Liao2004 ER - TY - JOUR AU - Louis, J. M. AU - Nashed, N. T. AU - Parris, K. D. AU - Kimmel, A. R. AU - Jerina, D. M. PY - 1994 DA - 1994// TI - Kinetics and mechanism of autoprocessing of human immunodeficiency virus type 1 protease from an analog of the Gag-Pol polyprotein JO - Proc Natl Acad Sci USA VL - 91 UR - https://doi.org/10.1073/pnas.91.17.7970 DO - 10.1073/pnas.91.17.7970 ID - Louis1994 ER - TY - JOUR AU - Pettit, S. C. AU - Gulnik, S. AU - Everitt, L. AU - Kaplan, A. H. PY - 2003 DA - 2003// TI - The dimer interfaces of protease and extra-protease domains influence the activation of protease and the specificity of GagPol cleavage JO - J Virol VL - 77 UR - https://doi.org/10.1128/JVI.77.1.366-374.2003 DO - 10.1128/JVI.77.1.366-374.2003 ID - Pettit2003 ER - TY - JOUR AU - Quillent, C. AU - Borman, A. M. AU - Paulous, S. AU - Dauguet, C. AU - Clavel, F. PY - 1996 DA - 1996// TI - Extensive regions of pol are required for efficient human immunodeficiency virus polyprotein processing and particle maturation JO - Virology VL - 219 UR - https://doi.org/10.1006/viro.1996.0219 DO - 10.1006/viro.1996.0219 ID - Quillent1996 ER - TY - JOUR AU - Zybarth, G. AU - Carter, C. PY - 1995 DA - 1995// TI - Domains upstream of the protease (PR) in human immunodeficiency virus type 1 Gag-Pol influence PR autoprocessing JO - J Virol VL - 69 ID - Zybarth1995 ER - TY - JOUR AU - Figueiredo, A. AU - Moore, K. L. AU - Mak, J. AU - Sluis-Cremer, N. AU - Bethune, M. P. AU - Tachedjian, G. PY - 2006 DA - 2006// TI - Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol JO - PLoS Pathog VL - 2 UR - https://doi.org/10.1371/journal.ppat.0020119 DO - 10.1371/journal.ppat.0020119 ID - Figueiredo2006 ER - TY - JOUR AU - Tachedjian, G. AU - Orlova, M. AU - Sarafianos, S. G. AU - Arnold, E. AU - Goff, S. P. PY - 2001 DA - 2001// TI - Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase JO - Proc Natl Acad Sci USA VL - 98 UR - https://doi.org/10.1073/pnas.121055998 DO - 10.1073/pnas.121055998 ID - Tachedjian2001 ER - TY - JOUR AU - Pan, Y. Y. AU - Wang, S. M. AU - Huang, K. J. AU - Chiang, C. C. AU - Wang, C. T. PY - 2012 DA - 2012// TI - Placement of leucine zipper motifs at the carboxyl terminus of HIV-1 protease significantly reduces virion production JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0032845 DO - 10.1371/journal.pone.0032845 ID - Pan2012 ER - TY - JOUR AU - Ludwig, C. AU - Leiherer, A. AU - Wagner, R. PY - 2008 DA - 2008// TI - Importance of protease cleavage sites within and flanking human immunodeficiency virus type 1 transframe protein p6* for spatiotemporal regulation of protease activation JO - J Virol VL - 82 UR - https://doi.org/10.1128/JVI.02353-07 DO - 10.1128/JVI.02353-07 ID - Ludwig2008 ER - TY - JOUR AU - Partin, K. AU - Zybarth, G. AU - Ehrlich, L. AU - DeCrombrugghe, M. AU - Wimmer, E. AU - Carter, C. PY - 1991 DA - 1991// TI - Deletion of sequences upstream of the proteinase improves the proteolytic processing of human immunodeficiency virus type 1 JO - Proc Natl Acad Sci USA VL - 88 UR - https://doi.org/10.1073/pnas.88.11.4776 DO - 10.1073/pnas.88.11.4776 ID - Partin1991 ER - TY - JOUR AU - Tessmer, U. AU - Krausslich, H. G. PY - 1998 DA - 1998// TI - Cleavage of human immunodeficiency virus type 1 proteinase from the N-terminally adjacent p6* protein is essential for efficient Gag polyprotein processing and viral infectivity JO - J Virol VL - 72 ID - Tessmer1998 ER - TY - JOUR AU - Paulus, C. AU - Ludwig, C. AU - Wagner, R. PY - 2004 DA - 2004// TI - Contribution of the Gag-Pol transframe domain p6* and its coding sequence to morphogenesis and replication of human immunodeficiency virus type 1 JO - Virology VL - 330 UR - https://doi.org/10.1016/j.virol.2004.09.013 DO - 10.1016/j.virol.2004.09.013 ID - Paulus2004 ER - TY - JOUR AU - Chatterjee, A. AU - Mridula, P. AU - Mishra, R. K. AU - Mittal, R. AU - Hosur, R. V. PY - 2005 DA - 2005// TI - Folding regulates autoprocessing of HIV-1 protease precursor JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.M412603200 DO - 10.1074/jbc.M412603200 ID - Chatterjee2005 ER - TY - JOUR AU - Ishima, R. AU - Torchia, D. A. AU - Louis, J. M. PY - 2007 DA - 2007// TI - Mutational and structural studies aimed at characterizing the monomer of HIV-1 protease and its precursor JO - J Biol Chem VL - 282 UR - https://doi.org/10.1074/jbc.M701304200 DO - 10.1074/jbc.M701304200 ID - Ishima2007 ER - TY - JOUR AU - Louis, J. M. AU - Clore, G. M. AU - Gronenborn, A. M. PY - 1999 DA - 1999// TI - Autoprocessing of HIV-1 protease is tightly coupled to protein folding JO - Nat Struct Biol VL - 6 UR - https://doi.org/10.1038/12327 DO - 10.1038/12327 ID - Louis1999 ER - TY - JOUR AU - Sadiq, S. K. AU - Noe, F. AU - Fabritiis, G. PY - 2012 DA - 2012// TI - Kinetic characterization of the critical step in HIV-1 protease maturation JO - Proc Natl Acad Sci USA VL - 109 UR - https://doi.org/10.1073/pnas.1210983109 DO - 10.1073/pnas.1210983109 ID - Sadiq2012 ER - TY - JOUR AU - Yu, F. -. H. AU - Huang, K. -. J. AU - Wang, C. -. T. PY - 2017 DA - 2017// TI - C-terminal HIV-1 transframe p6* tetrapeptide blocks enhanced Gag cleavage incurred by leucine zipper replacement of a deleted p6* domain JO - J Virol VL - 91 UR - https://doi.org/10.1128/JVI.00103-17 DO - 10.1128/JVI.00103-17 ID - Yu2017 ER - TY - JOUR AU - Ratner, L. AU - Haseltine, W. AU - Patarca, R. AU - Livak, K. J. AU - Starcich, B. AU - Josephs, S. F. AU - Doran, E. R. AU - Rafalski, J. A. AU - Whitehorn, E. A. AU - Baumeister, K. PY - 1985 DA - 1985// TI - Complete nucleotide sequence of the AIDS virus JO - HTLV-III. Nature VL - 313 UR - https://doi.org/10.1038/313277a0 DO - 10.1038/313277a0 ID - Ratner1985 ER - TY - JOUR AU - Page, K. A. AU - Landau, N. R. AU - Littman, D. R. PY - 1990 DA - 1990// TI - Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity JO - J Virol VL - 64 ID - Page1990 ER - TY - JOUR AU - Yu, F. -. H. AU - Chou, T. -. A. AU - Liao, W. -. H. AU - Huang, K. -. J. AU - Wang, C. -. T. PY - 2015 DA - 2015// TI - Gag-Pol transframe domain p6* is essential for HIV-1 protease-mediated virus maturation JO - PLoS ONE VL - 10 UR - https://doi.org/10.1371/journal.pone.0127974 DO - 10.1371/journal.pone.0127974 ID - Yu2015 ER - TY - JOUR AU - Chen, S. -. W. AU - Chiu, H. -. C. AU - Liao, W. -. H. AU - Wang, F. -. D. AU - Chen, S. S. L. AU - Wang, C. -. T. PY - 2004 DA - 2004// TI - The virus-associated human immunodeficiency virus type 1 Gag-Pol carrying an active protease domain in the matrix region is severely defective both in autoprocessing and in trans processing of gag particles JO - Virology VL - 318 UR - https://doi.org/10.1016/j.virol.2003.08.043 DO - 10.1016/j.virol.2003.08.043 ID - Chen2004 ER - TY - JOUR AU - Boles, E. AU - Miosga, T. PY - 1995 DA - 1995// TI - A rapid and highly efficient method for PCR-based site-directed mutagenesis using only one new primer JO - Curr Genet VL - 28 UR - https://doi.org/10.1007/BF00315788 DO - 10.1007/BF00315788 ID - Boles1995 ER - TY - JOUR AU - Chiu, H. -. C. AU - Yao, S. -. Y. AU - Wang, C. -. T. PY - 2002 DA - 2002// TI - Coding sequences upstream of the human immunodeficiency virus type 1 reverse transcriptase domain in Gag-Pol are not essential for incorporation of the Pr160gag-pol into virus particles JO - J Virol VL - 76 UR - https://doi.org/10.1128/JVI.76.7.3221-3231.2002 DO - 10.1128/JVI.76.7.3221-3231.2002 ID - Chiu2002 ER - TY - JOUR AU - Yee, J. K. AU - Friedmann, T. AU - Burns, J. C. PY - 1994 DA - 1994// TI - Generation of high-titer pseudotyped retrovirus with very broad host range JO - Methods in Cell Biology VL - 43 UR - https://doi.org/10.1016/S0091-679X(08)60600-7 DO - 10.1016/S0091-679X(08)60600-7 ID - Yee1994 ER - TY - JOUR AU - Chen, Y. L. AU - Ts’ai, P. W. AU - Yang, C. C. AU - Wang, C. T. PY - 1997 DA - 1997// TI - Generation of infectious virus particles by transient co-expression of human immunodeficiency virus type 1 gag mutants JO - J Gen Virol VL - 78 UR - https://doi.org/10.1099/0022-1317-78-10-2497 DO - 10.1099/0022-1317-78-10-2497 ID - Chen1997 ER - TY - JOUR AU - Chiang, C. -. C. AU - Wang, S. -. M. AU - Tseng, Y. -. T. AU - Huang, K. -. J. AU - Wang, C. -. T. PY - 2009 DA - 2009// TI - Mutations at human immunodeficiency virus type 1 reverse transcriptase tryptophan repeat motif attenuate the inhibitory effect of efavirenz on virus production JO - Virology VL - 383 UR - https://doi.org/10.1016/j.virol.2008.10.027 DO - 10.1016/j.virol.2008.10.027 ID - Chiang2009 ER - TY - JOUR AU - Ferris, A. L. AU - Hizi, A. AU - Showalter, S. D. AU - Pichuantes, S. AU - Babe, L. AU - Craik, C. S. AU - Hughes, S. H. PY - 1990 DA - 1990// TI - Immunologic and proteolytic analysis of HIV-1 reverse transcriptase structure JO - Virology VL - 175 UR - https://doi.org/10.1016/0042-6822(90)90430-Y DO - 10.1016/0042-6822(90)90430-Y ID - Ferris1990 ER - TY - JOUR AU - Hizi, A. AU - McGill, C. AU - Hughes, S. H. PY - 1988 DA - 1988// TI - Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants JO - Proc Natl Acad Sci VL - 85 UR - https://doi.org/10.1073/pnas.85.4.1218 DO - 10.1073/pnas.85.4.1218 ID - Hizi1988 ER - TY - JOUR AU - Chiu, H. -. C. AU - Wang, F. -. D. AU - Chen, Y. -. M. A. AU - Wang, C. -. T. PY - 2006 DA - 2006// TI - Effects of human immunodeficiency virus type 1 transframe protein p6* mutations on viral protease-mediated Gag processing JO - J Gen Virol VL - 87 UR - https://doi.org/10.1099/vir.0.81601-0 DO - 10.1099/vir.0.81601-0 ID - Chiu2006 ER - TY - JOUR AU - Cherry, E. AU - Liang, C. AU - Rong, L. AU - Quan, Y. AU - Inouye, P. AU - Li, X. AU - Morin, N. AU - Kotler, M. AU - Wainberg, M. A. PY - 1998 DA - 1998// TI - Characterization of human immunodeficiency virus type-1 (HIV-1) particles that express protease-reverse transcriptase fusion proteins11 JO - J Mol Biol VL - 284 UR - https://doi.org/10.1006/jmbi.1998.1968 DO - 10.1006/jmbi.1998.1968 ID - Cherry1998 ER - TY - JOUR AU - Pettit, S. C. AU - Simsic, J. AU - Loeb, D. D. AU - Everitt, L. AU - Hutchison, C. A. AU - Swanstrom, R. PY - 1991 DA - 1991// TI - Analysis of retroviral protease cleavage sites reveals two types of cleavage sites and the structural requirements of the P1 amino acid JO - J Biol Chem VL - 266 ID - Pettit1991 ER - TY - JOUR AU - Tang, C. AU - Louis, J. M. AU - Aniana, A. AU - Suh, J. Y. AU - Clore, G. M. PY - 2008 DA - 2008// TI - Visualizing transient events in amino-terminal autoprocessing of HIV-1 protease JO - Nature VL - 455 UR - https://doi.org/10.1038/nature07342 DO - 10.1038/nature07342 ID - Tang2008 ER -