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Fig. 3 | Retrovirology

Fig. 3

From: Aged Chinese-origin rhesus macaques infected with SIV develop marked viremia in absence of clinical disease, inflammation or cognitive impairment

Fig. 3

No elevation of hallmarks of chronic inflammation during lentiviral infection in aged SIV-infected Chinese macaques. IL-18 is elevated in aged SIV-infected macaques of Chinese origin during acute infection, but other hallmarks of chronic inflammation during lentiviral infection remain stable. Median plasma concentrations of soluble CD14 (sCD14) (a), IL-6 (b), IL-18 (c), CXCL10 (d), and TNF-α (e) at 0, 2, 4 wpi and 34 or 36 wpi or necropsy (34/36/nec). 0 wpi represents baseline, 2 and 4 wpi represent acute infection and 34/36/nec represent chronic infection. Kruskal–Wallis tests were used to analyze differences between groups. *P < 0.05. **P < 0.01

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Retrovirology

ISSN: 1742-4690

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