Fig. 2

Neither infection or CART impacted performance on a speeded motor task in aged Chinese macaques. Comparison of median response times and accuracy did not show significant differences. Shown here are between group comparisons of mean ± standard error speeded motor performance response time (a) and accuracy (b). Analyses for response time and accuracy were binned by every 2 wpi over the course of training period, SIVmac251 or mock infection and CART. Differences between SIV-infection without CART versus SIV-infection with CART (SIV-Infected), Mock-infection without CART versus Mock-infection with CART (No Infection), SIV-infected versus Mock-Infected (Infection vs Noninfection), and CART versus PBS (treatment vs no treatment) are shown for a and b. Kruskal–Wallis tests were used to compare results displayed in each graph, but no statistically significant differences were found. The green shaded area represents the period macaques received CART