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Table 2 Profiling functional Fc effector functions

From: Systems serology: profiling vaccine induced humoral immunity against HIV

 
Effector Complement activation ADCP ADCC Antibody dependent Cytokine secretion Antibody dependent Chemokine secretion Antibody dependent Virus Inhibition
NK cells + + + +
Neutrophils + + + + ND
Monocytes + + + + +
Dendritic cells + + + ND
Complement + ND ND ND ND +
Examples of Assays Complement assay
ELISA
Bead assay
Virion assay
Cr51 Release
RFADCC
GranToxiLux
Luciferase ADCC
BVADCC
ICS ICS ADCVI
References [86, 108] [10, 62, 63, 109,110,111] [28, 112,113,114,115,116,117] [31, 118] [31] [13]