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Table 2 Changes in nucleotide composition and total number of mutations for codon modification of regions 22-261 and 22-378 in gag

From: Increasing the CpG dinucleotide abundance in the HIV-1 genomic RNA inhibits viral replication

Construct % A % C % G % T Total UpA Total CpG Total number mutations relative to wild type
WT 22-261 38 17 23 22 23 4  
CM 22-261 18 36 32 15 3 22 80
CM 22-261lowCpG 24 27 34 15 5 4 59
CpG 22-261 32 25 22 21 19 22 21
WT 22-378 42 17 24 18 29 4  
CM 22-378 22 35 32 12 3 30 109
CM 22-378lowCpG 28 26 33 13 7 4 79
CpG 22-378 36 25 22 17 23 30 30