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Fig. 8 | Retrovirology

Fig. 8

From: The HIV-1 integrase-LEDGF allosteric inhibitor MUT-A: resistance profile, impairment of virus maturation and infectivity but without influence on RNA packaging or virus immunoreactivity

Fig. 8

IL-5, IL-6, IL-10, IL-13, MIP-1α, MCP-1 and IP-10 secretion induced by MUT-A-HIV-1-exposed autologous MDDCs. Cytokine and chemokine secretion in response to autologous MDDCs exposed to wt HIV-1 (NL4-3 DMSO) or MUT-A-inactivated HIV-1 (MUT-A 1 µM) in supernatants from a 6-day co-culture was assessed in duplicates by Luminex assay. Graph representing mean ± SD concentrations (pg/mL) of IL-10 (a), IL-6 (b), IL-13 (c), MIP-1α (d), MCP-1 (e), IL-5 (f) and IP-10 (g) analyzed after three different co-cultures

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