Fig. 6
Post-binding neutralization activity. The neutralization activities of anti-CD4i mAbs against BaL (a) and JR-FL (b) after attachment of virus and target cell were analyzed. The neutralizing activities of IgGs are shown as open circle, and scFvs are shown as closed square. scFvs targeting the CD4i epitopes inhibited virus infection after virus-attachment to the target cells against both viruses. The statistical significance was calculated using a Student’s t test (*P < 0.05, **P < 0.005, ***P < 0.0005)