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Fig. 5 | Retrovirology

Fig. 5

From: Unique binding modes for the broad neutralizing activity of single-chain variable fragments (scFv) targeting CD4-induced epitopes

Fig. 5

Pre-binding neutralization activity. The neutralization activities of anti-CD4i mAbs against BaL (a) and JR-FL (b) before the attachment of virus and target cell were analyzed. The pseudo-virus infected the target cells after pre-incubation in the presence of the neutralizing mAbs. Anti-CD4bs mAb, b12 (10 μg/ml), anti-V3 mAb, KD-247 and anti-CD4i mAbs (100 μg/ml) were used. The neutralization activities of the IgGs (black) and scFvs (gray) were standardized by the amount of p24

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Retrovirology

ISSN: 1742-4690

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