Fig. 4
From: Identification of a homogenous structural basis for oligomerization by retroviral Rev-like proteins
Ancestral inference of coiled-coils in Rev proteins of primate lentiviruses. Analysis was performed using the Env-based tree shown in Fig. 3. Black area of filled circles indicates the probability of Rev coiled-coils being present at that node; red arrow points to a single major transition from higher to lower probability of the coiled-coil signal in the phylogeny (0.60–0.12 probability). The probability of a Rev coiled-coil in the ancestral node of SIVsmm/HIV-2 and SIVagm/rcm (0.99), and the overall probability of an ancestral Rev coiled-coil for all lentiviruses (0.98) are indicated