Fig. 2

Antibody mapping of anti-HERV-K (HML-2) responses in healthy donors. Sera from 8 seronegative low risk healthy donors (SNLR) were used for antibody epitope identification by ELISA. The 7 sub-units: matrix (MA), SP1, p15, capsid (CA), nucleocapsid (NC) and QP 1 and 2 are represented by 164 redundant 15mers named by their number corresponding to their rank in the list. The lines represent the average of the 8 individuals and duplicate signals (OD). Background was determined by the average of OD from each peptide. The statistical significance between the different groups was established using a Kruskal–Wallis and Dunn’s Multiple Comparison test and a p value <0.05 was considered as significant. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001