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Fig. 1 | Retrovirology

Fig. 1

From: Granulocytic myeloid-derived suppressor cells suppress virus-specific CD8+ T cell responses during acute Friend retrovirus infection

Fig. 1

MDSCs expand during acute FV infection. B6 mice were infected i.v. with 20,000 SFFU of FV or left un-infected, and MDSC numbers were measured using flow cytometry. The total spleen cells were analyzed at various time points post infection. a The numbers of Ly6Ghigh Ly6Clow and b Ly6G Ly6Chigh per 1 × 106 live splenocytes and the frequencies of c CD80 expression on the surface of Ly6Ghigh Ly6Clow and Ly6G Ly6Chigh cells are displayed. At least 7 mice per group from five independent experiments were analyzed. Bars represent means with SD. For statistical analysis a Dunn’s test with the Benjamini–Hochberg correction for multiple testing (b) and an unpaired t test (c) were performed (*<0.05; **<0.005)

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