Fig. 1

MDSCs expand during acute FV infection. B6 mice were infected i.v. with 20,000 SFFU of FV or left un-infected, and MDSC numbers were measured using flow cytometry. The total spleen cells were analyzed at various time points post infection. a The numbers of Ly6G^high Ly6C^low and b Ly6G⁻ Ly6C^high per 1 × 10⁶ live splenocytes and the frequencies of c CD80 expression on the surface of Ly6G^high Ly6C^low and Ly6G⁻ Ly6C^high cells are displayed. At least 7 mice per group from five independent experiments were analyzed. Bars represent means with SD. For statistical analysis a Dunn’s test with the Benjamini–Hochberg correction for multiple testing (b) and an unpaired t test (c) were performed (*<0.05; **<0.005)