Fig. 6
From: Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells
Schematic overview of LV restriction and strategies to improve murine iPSC transduction. Primary fibroblasts of murine origin were efficiently transduced with LV. After reprogramming, iPSC exhibited a potent LV restriction phenotype, which was decreased by high vector amounts, HIV-1 CypA-independent capsid mutants, treatment with CSA during transduction or iPSC differentiation