Fig. 5

Longitudinal analysis of HIV-1 proviral env sequences obtained from subjects PEC52 (a, d), EEC42 (b, e) and VC05 (c, f) between 2000–2013, 2000–2012 and 2000–2011, respectively. a–c ML phylogenetic trees for each individual are shown, in which horizontal branch lengths are drawn to scale with the bar at the bottom indicating nucleotide substitutions per site. d–f Plots of the root-to-tip distance against sequence sampling time are shown below each subject tree. The slope, coefficient of regression and X intercept of linear regression analysis is indicated. The colors of the circles in phylogenetic trees and plots represent the sampling year at which sequences were obtained