Fig. 1

Clinical follow-up of the 23 HIV-1 controllers. Plasma RNA viral load (copies/mL, circles) and CD4⁺ T cell counts (cells/µL, squares) values over time (years) are shown on the left and right Y axis respectively. RNA viral loads below or above the detection limit are colored black and red, respectively. The limit of detection of RNA viral load varied over time according to the methodology used. Shaded areas indicate the time points selected in this study (gray) and previously (green) [17] for the DNA quasispecies analysis. Patient identification is shown in the upper left corner of each graph