Fig. 8
From: Molecular mechanisms by which HERV-K Gag interferes with HIV-1 Gag assembly and particle infectivity
Chimeric Gag constructs containing a part of CA partially colocalize with HIV-1 Gag at the PM. HeLa cells coexpressing YFP-tagged HERV-K Gag, MLV Gag or chimeric Gag (green) and mRFP-tagged HIV-1 Gag (red) proteins were examined using fluorescence microscopy at 16 h after cotransfection (a). Images acquired at the mid-section of the cells. b The R strength of correlation between fluorescence intensities of pairs of indicated Gag-fluorescent protein chimeras was calculated for cells coexpressing these Gag proteins. P values were determined using a Student’s t test. *P < 0.01; ***P < 0.0001; n.s. not significant