Fig. 1
From: Molecular mechanisms by which HERV-K Gag interferes with HIV-1 Gag assembly and particle infectivity
Coassembly of HERV-K Gag changes properties of HIV-1 particles. HeLa cells expressing HIV-1 molecular clone (a), HERV-K Gag-FLAG (b), or HIV-1 molecular clone and HERV-K Gag-FLAG (c) were analyzed by transmission electron microscopy at 16Â h post-transfection. Bars in frame 1, 200Â nm; bars in frame 2 and 3, 100Â nm. d, e The sizes of VLPs or mature particles, which are released from transfected cells, were measured using images of transmission electron microscopy. Total numbers of VLPs examined are 232, 239, and 256 for cultures expressing HIV-1 alone, HERV-K Gag-FLAG alone, and HIV-1 and HERV-K Gag-FLAG, respectively